Top 11 Creams for Severe Diaper Rash

Thanks in part to their propensity for GI issues, babies with and recovering from neonatal abstinence syndrome (NAS) are prone to more severe cases of diaper rash. Research on babies with NAS has shown zinc oxide barrier creams to be an effective part of treating diaper rash. In this post, we will detail the top zinc oxide creams as recommended by our caregiver support group.

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Diaper Creams

Triple Paste


Barrier Creams

You may also find it helpful to add a layer of barrier cream on top of the zinc oxide cream, or to alternate barrier cream with zinc oxide cream at each diaper change. This is especially helpful if your baby has open sores or raw skin on their bottom from GI issues during and after withdrawal. Below are some recommended alternatives to popular barrier creams like Aquaphor and Vaseline. Each of these contains gentler and more effective ingredients for delicate and denuded skin.

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